RASSF2 and RASSF5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		RASSF2	RASSF5
Description		Ras association domain family member 2	Ras association domain family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Protein-containing Complex	Nucleus Cytoplasm Microtubule
	Molecular Function	Protein Kinase Activity Protein Binding	Protein Binding Small GTPase Binding Metal Ion Binding
	Biological Process	Skeletal System Development Ossification Protein Phosphorylation Cell Cycle Signal Transduction Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Bone Remodeling Homeostasis Of Number Of Cells Protein Stabilization Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling	Apoptotic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Suicide attempt severity in mood disorders ( 33783297) Systemic lupus erythematosus ( 24871463)	Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		11 interacting genes: HRAS IRAK1 KDM1A KIZ KRAS NKX2-2 PRMT3 PRMT6 RASSF5 S100Z SUV39H1	30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28
Entrez ID		9770	83593
HPRD ID		15218	06117
Ensembl ID		ENSG00000101265	ENSG00000266094
Uniprot IDs		P50749	A8K5F3 Q8WWW0
PDB IDs			4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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