RASSF5 and ADH6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RASSF5	ADH6
Description		Ras association domain family member 5	alcohol dehydrogenase 6 (class V)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Metal Ion Binding	Alcohol Dehydrogenase (NAD+) Activity Alcohol Dehydrogenase Activity, Zinc-dependent NAD-retinol Dehydrogenase Activity Zinc Ion Binding
	Biological Process	Apoptotic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus	Ethanol Oxidation Retinol Metabolic Process Retinoic Acid Metabolic Process Response To Ethanol
Pathways			Ethanol oxidation
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)	Alcohol dependence ( 23456092) Alcohol use disorder (consumption score) ( 30940813 30336701) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Aspartate aminotransferase levels ( 33547301) Esophageal cancer ( 19698717) QRS duration ( 23534349) Regular attendance at a pub or social club ( 29970889) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28	9 interacting genes: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 SLC39A8 TNIP1
Entrez ID		83593	130
HPRD ID		06117	00067
Ensembl ID		ENSG00000266094	ENSG00000172955
Uniprot IDs		A8K5F3 Q8WWW0	P28332 Q8IUN7
PDB IDs		4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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