RASSF2 and PRMT3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		RASSF2	PRMT3
Description		Ras association domain family member 2	protein arginine methyltransferase 3
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Protein-containing Complex	Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Protein Binding	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding
	Biological Process	Skeletal System Development Ossification Protein Phosphorylation Cell Cycle Signal Transduction Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Bone Remodeling Homeostasis Of Number Of Cells Protein Stabilization Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation Negative Regulation Of Retinoic Acid Biosynthetic Process
Pathways			RMTs methylate histone arginines Protein methylation
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS		Refractive error ( 32231278) Suicide attempt severity in mood disorders ( 33783297) Systemic lupus erythematosus ( 24871463)	Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		11 interacting genes: HRAS IRAK1 KDM1A KIZ KRAS NKX2-2 PRMT3 PRMT6 RASSF5 S100Z SUV39H1	10 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 STAT1 TSC22D2
Entrez ID		9770	10196
HPRD ID		15218	11934
Ensembl ID		ENSG00000101265	ENSG00000185238
Uniprot IDs		P50749	O60678 Q8WUV3
PDB IDs			2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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