PRMT3 and RASSF2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		PRMT3	RASSF2
Description		protein arginine methyltransferase 3	Ras association domain family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Kinetochore Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding	Protein Kinase Activity Protein Binding
	Biological Process	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation Negative Regulation Of Retinoic Acid Biosynthetic Process	Skeletal System Development Ossification Protein Phosphorylation Cell Cycle Signal Transduction Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Bone Remodeling Homeostasis Of Number Of Cells Protein Stabilization Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		RMTs methylate histone arginines Protein methylation
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)	Refractive error ( 32231278) Suicide attempt severity in mood disorders ( 33783297) Systemic lupus erythematosus ( 24871463)
Interacting Genes		10 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 STAT1 TSC22D2	11 interacting genes: HRAS IRAK1 KDM1A KIZ KRAS NKX2-2 PRMT3 PRMT6 RASSF5 S100Z SUV39H1
Entrez ID		10196	9770
HPRD ID		11934	15218
Ensembl ID		ENSG00000185238	ENSG00000101265
Uniprot IDs		O60678 Q8WUV3	P50749
PDB IDs		2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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