CD59 and NCR3

Number of citations of the paper that reports this interaction (PubMedID 14635045)
24

Data Source:
HPRD (in vivo, in vitro)

		CD59	NCR3
Description		CD59 molecule (CD59 blood group)	natural cytotoxicity triggering receptor 3
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Endoplasmic Reticulum Membrane Plasma Membrane Focal Adhesion Cell Surface ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Anchored Component Of External Side Of Plasma Membrane Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Complement Binding Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Activation Of Membrane Attack Complex Cell Surface Receptor Signaling Pathway Blood Coagulation Regulation Of Complement Activation Regulation Of Complement-dependent Cytotoxicity	Immune Response-activating Cell Surface Receptor Signaling Pathway Inflammatory Response Immune Response Cell Recognition Natural Killer Cell Activation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER Neutrophil degranulation COPI-mediated anterograde transport Regulation of Complement cascade	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body size at age 10 ( 32376654) Chronotype ( 30696823) Fruit consumption ( 32066663) Morning person ( 30696823)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Hypertension ( 30226566) Inflammatory bowel disease ( 28067908) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 28166213) Malaria ( 31844061) Pulmonary function ( 21946350) Pulmonary function (smoking interaction) ( 23284291) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Takayasu arteritis ( 25604533) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Weight ( 19079260)
Interacting Genes		19 interacting genes: BDNF C8A C9 CCR2 CD2 CD8A CD9 CHRM4 EGFR FAM209A GNAI3 NAT8 NCR1 NCR3 SLC13A1 SLC6A8 SMAD4 SRC WFS1	5 interacting genes: BAG6 CD247 CD59 FAM209A FCER1G
Entrez ID		966	259197
HPRD ID		00117	11384
Ensembl ID		ENSG00000085063	ENSG00000204475
Uniprot IDs		P13987 Q6FHM9	O14931 Q05D23
PDB IDs		1CDQ 1CDR 1CDS 1ERG 1ERH 2J8B 2OFS 2UWR 2UX2 4BIK 5IMT 5IMY 6ZD0	3NOI 3PV6 6YJP
Enriched GO Terms of Interacting Partners?
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