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CD59

Description CD59 molecule (CD59 blood group)
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Extracellular Space
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Focal Adhesion
  • Cell Surface
  • ER To Golgi Transport Vesicle Membrane
  • Membrane
  • Transport Vesicle
  • Anchored Component Of External Side Of Plasma Membrane
  • Vesicle
  • Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
  • Specific Granule Membrane
  • Extracellular Exosome
  • Tertiary Granule Membrane
Molecular Function
  • Complement Binding
  • Protein Binding
Biological Process
  • Negative Regulation Of Activation Of Membrane Attack Complex
  • Cell Surface Receptor Signaling Pathway
  • Blood Coagulation
  • Regulation Of Complement Activation
  • Regulation Of Complement-dependent Cytotoxicity
Pathways
  • COPII-mediated vesicle transport
  • Cargo concentration in the ER
  • Neutrophil degranulation
  • COPI-mediated anterograde transport
  • Regulation of Complement cascade
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Body size at age 10 ( 32376654)
  • Chronotype ( 30696823)
  • Fruit consumption ( 32066663)
  • Morning person ( 30696823)
Interacting Genes 19 interacting genes: BDNF C8A C9 CCR2 CD2 CD8A CD9 CHRM4 EGFR FAM209A GNAI3 NAT8 NCR1 NCR3 SLC13A1 SLC6A8 SMAD4 SRC WFS1
Entrez ID 966
HPRD ID 00117
Ensembl ID ENSG00000085063
Uniprot IDs P13987 Q6FHM9
PDB IDs 1CDQ 1CDR 1CDS 1ERG 1ERH 2J8B 2OFS 2UWR 2UX2 4BIK 5IMT 5IMY 6ZD0
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025