PRDX6 and ORM2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PRDX6	ORM2
Description		peroxiredoxin 6	orosomucoid 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Thioredoxin Peroxidase Activity Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding 1-acylglycerophosphocholine O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Oxidant Detoxification	Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production
Pathways		Detoxification of Reactive Oxygen Species Neutrophil degranulation	Platelet degranulation Neutrophil degranulation
Drugs		2-(N-morpholino)ethanesulfonic acid Copper	Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Adult body size ( 32376654) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)	Blood protein levels ( 29875488)
Interacting Genes		22 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 MX1 NCF2 NR4A1 ORM2 PAXIP1 PPARD PSMD8 RARA SFTPA1 STH SUMO2 SUMO4 TERF1 TERF2IP UCHL5 YWHAE	4 interacting genes: BBS5 CYP39A1 PRDX6 STK3
Entrez ID		9588	5005
HPRD ID		03817	00725
Ensembl ID		ENSG00000117592	ENSG00000228278
Uniprot IDs		P30041 V9HWC7	P19652
PDB IDs		1PRX 5B6M 5B6N	3APU 3APV 3APW 3APX
Enriched GO Terms of Interacting Partners?
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