ORM2 and CYP39A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ORM2	CYP39A1
Description		orosomucoid 2	cytochrome P450 family 39 subfamily A member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function		Iron Ion Binding Steroid 7-alpha-hydroxylase Activity Steroid Hydroxylase Activity Oxysterol 7-alpha-hydroxylase Activity Heme Binding 24-hydroxycholesterol 7alpha-hydroxylase Activity
	Biological Process	Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production	Bile Acid Biosynthetic Process Cholesterol Catabolic Process Digestion Sterol Metabolic Process Cholesterol Homeostasis
Pathways		Platelet degranulation Neutrophil degranulation	Synthesis of bile acids and bile salts via 24-hydroxycholesterol Endogenous sterols
Drugs		Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 29875488)	Normal facial asymmetry (deformation magnitude) ( 30631343)
Interacting Genes		4 interacting genes: BBS5 CYP39A1 PRDX6 STK3	4 interacting genes: GLUL ORM2 SERINC1 SMYD3
Entrez ID		5005	51302
HPRD ID		00725	07067
Ensembl ID		ENSG00000228278	ENSG00000146233
Uniprot IDs		P19652	A0A087WTD2 B7Z786 Q9NYL5
PDB IDs		3APU 3APV 3APW 3APX
Enriched GO Terms of Interacting Partners?
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