ORM2 and PRDX6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ORM2	PRDX6
Description		orosomucoid 2	peroxiredoxin 6
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function		Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Thioredoxin Peroxidase Activity Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding 1-acylglycerophosphocholine O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production	Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Oxidant Detoxification
Pathways		Platelet degranulation Neutrophil degranulation	Detoxification of Reactive Oxygen Species Neutrophil degranulation
Drugs		Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form	2-(N-morpholino)ethanesulfonic acid Copper
Diseases
GWAS		Blood protein levels ( 29875488)	Adult body size ( 32376654) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)
Interacting Genes		4 interacting genes: BBS5 CYP39A1 PRDX6 STK3	22 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 MX1 NCF2 NR4A1 ORM2 PAXIP1 PPARD PSMD8 RARA SFTPA1 STH SUMO2 SUMO4 TERF1 TERF2IP UCHL5 YWHAE
Entrez ID		5005	9588
HPRD ID		00725	03817
Ensembl ID		ENSG00000228278	ENSG00000117592
Uniprot IDs		P19652	P30041 V9HWC7
PDB IDs		3APU 3APV 3APW 3APX	1PRX 5B6M 5B6N
Enriched GO Terms of Interacting Partners?
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