CHD1L and XRCC1

Number of citations of the paper that reports this interaction (PubMedID 33053171)
0

Data Source:
BioGRID (fluorescent resonance energy transfer, fluorescent resonance energy transfer)

		CHD1L	XRCC1
Description		chromodomain helicase DNA binding protein 1 like	X-ray repair cross complementing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Nucleolus ERCC4-ERCC1 Complex
	Molecular Function	Nucleotide Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity	Protein Binding Enzyme Binding Oxidized DNA Binding 3' Overhang Single-stranded DNA Endodeoxyribonuclease Activity
	Biological Process	DNA Repair Chromatin Remodeling Cellular Response To DNA Damage Stimulus DNA Duplex Unwinding	Single Strand Break Repair Response To Hypoxia Base-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Xenobiotic Stimulus Response To Organic Substance Negative Regulation Of Protein ADP-ribosylation Cerebellum Morphogenesis Hippocampus Development Response To Hydroperoxide Voluntary Musculoskeletal Movement Telomeric DNA-containing Double Minutes Formation Positive Regulation Of Single Strand Break Repair Positive Regulation Of DNA Ligase Activity Negative Regulation Of Protection From Non-homologous End Joining At Telomere Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Pathways		Formation of Incision Complex in GG-NER Dual Incision in GG-NER	Resolution of AP sites via the single-nucleotide replacement pathway APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway HDR through MMEJ (alt-NHEJ) Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS		Height ( 31562340) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25760438)	Apolipoprotein B levels ( 32203549) Height ( 31562340) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		9 interacting genes: BAALC CTCF NR4A1 PARP1 PDE4DIP SCYL1 SRPK2 TRIM33 XRCC1	20 interacting genes: APEX1 APLF APTX BRCA1 BTRC CHD1L CSNK2A1 CSNK2A2 LIG3 NEIL1 OGG1 PARP1 PARP2 PCNA PNKP POLB PSMD8 RNF146 TOPORS UBE2I
Entrez ID		9557	7515
HPRD ID		09880	01909
Ensembl ID		ENSG00000131778	ENSG00000073050
Uniprot IDs		A0A0A0MRH8 A0A0A0MSH9 Q86WJ1	B2RCY5 P18887 Q59HH7
PDB IDs		6ZHX 6ZHY	1CDZ 1XNA 1XNT 2D8M 2W3O 3K75 3K77 3LQC 5E6Q 5W7X 5W7Y 6WH1 6WH2
Enriched GO Terms of Interacting Partners?
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