SYTL4 and OSBPL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYTL4	OSBPL3
Description		synaptotagmin like 4	oxysterol binding protein like 3
Image
GO Annotations	Cellular Component	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Phospholipid Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Plasma Membrane Repair Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair	Bile Acid Biosynthetic Process Sterol Transport
Pathways		Platelet degranulation	Synthesis of bile acids and bile salts
Drugs		Insulin pork
Diseases
GWAS		Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1	26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835
Entrez ID		94121	26031
HPRD ID		06735	09474
Ensembl ID		ENSG00000102362	ENSG00000070882
Uniprot IDs		A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24	Q9H4L5
PDB IDs		2CSZ 3FDW 5X6T	7CYZ
Enriched GO Terms of Interacting Partners?
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