OSBPL3 and ZNF48

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OSBPL3	ZNF48
Description		oxysterol binding protein like 3	zinc finger protein 48
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum	Nucleus
	Molecular Function	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Bile Acid Biosynthetic Process Sterol Transport	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	19 interacting genes: APOBEC3C BYSL CEP55 EIF3E FNDC11 GOLGA2 GOLGA6L9 HOOK2 MORF4L2 MTUS2 OGT OSBPL3 PRPF31 SF3B4 TACC1 TLE5 TRIM41 ZNF774 ZNF792
Entrez ID		26031	197407
HPRD ID		09474	15836
Ensembl ID		ENSG00000070882	ENSG00000180035
Uniprot IDs		Q9H4L5	A0A087WVT1 Q96MX3
PDB IDs		7CYZ
Enriched GO Terms of Interacting Partners?
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