OSBPL3 and RALGPS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OSBPL3	RALGPS2
Description		oxysterol binding protein like 3	Ral GEF with PH domain and SH3 binding motif 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Bile Acid Biosynthetic Process Sterol Transport	Small GTPase Mediated Signal Transduction Regulation Of Ral Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 32771030)
Interacting Genes		26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	5 interacting genes: IFT20 OSBPL3 YWHAB YWHAG YWHAZ
Entrez ID		26031	55103
HPRD ID		09474	15206
Ensembl ID		ENSG00000070882	ENSG00000116191
Uniprot IDs		Q9H4L5	Q86X27
PDB IDs		7CYZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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