SLC9A3R2 and ADORA2B

Number of citations of the paper that reports this interaction (PubMedID 12080047)
37

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SLC9A3R2	ADORA2B
Description		SLC9A3 regulator 2	adenosine A2b receptor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding	G Protein-coupled Adenosine Receptor Activity Protein Binding
	Biological Process	Protein-containing Complex Assembly Protein Localization To Plasma Membrane	G Protein-coupled Adenosine Receptor Signaling Pathway Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity JNK Cascade Excretion
Pathways			Adenosine P1 receptors G alpha (s) signalling events Surfactant metabolism ADORA2B mediated anti-inflammatory cytokines production
Drugs			Caffeine Theophylline Adenosine Enprofylline Defibrotide CVT-6883
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)	HDL cholesterol levels in HIV infection ( 33109212) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		43 interacting genes: ABCC4 ACE2 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR IFT140 KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAFAZZIN TBC1D10A TRAF4 WWP2 WWTR1	7 interacting genes: ADA DCC EZR NTN1 SLC9A3R2 TPD52L2 ZNF267
Entrez ID		9351	136
HPRD ID		05946	15971
Ensembl ID		ENSG00000065054	ENSG00000170425
Uniprot IDs		Q15599	P29275
PDB IDs		2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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