GPR37L1 and THSD7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR37L1	THSD7B
Description		G protein-coupled receptor 37 like 1	thrombospondin type 1 domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Actin Cytoskeleton Reorganization
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)	Albumin-globulin ratio ( 29403010) Aluminium levels ( 26025379) Daytime sleep phenotypes ( 27126917) Liver enzyme levels (aspartate transaminase) ( 24124411) Machado-Joseph disease (age at onset) ( 32205469) Multiple system atrophy ( 27629089) Non-albumin protein levels ( 29403010) Non-small cell lung cancer ( 23144319) Pancreatic cancer ( 20686608) Problematic alcohol use ( 32451486) Prudent dietary pattern ( 28644415) Regular attendance at a gym or sports club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 30224653) Tooth agenesis (third molar) ( 24172245) Urinary albumin-to-creatinine ratio ( 26631737) Weight ( 28552196)
Interacting Genes		52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B	25 interacting genes: AQP6 ARL13B CISD2 DARS2 FAM209A FKBP7 GJA8 GPR101 GPR152 GPR37L1 KCNJ6 KIR3DL1 LYVE1 MFSD14B MTIF3 PEX12 PIGP PLEKHO1 RANBP10 SLC14A1 SLC30A8 SPACA1 STOM SYT2 TMX2
Entrez ID		9283	80731
HPRD ID		13603	19009
Ensembl ID		ENSG00000170075	ENSG00000144229
Uniprot IDs		O60883	Q9C0I4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?