THSD7B and MTIF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		THSD7B	MTIF3
Description		thrombospondin type 1 domain containing 7B	mitochondrial translational initiation factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Mitochondrion
	Molecular Function		Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding
	Biological Process	Actin Cytoskeleton Reorganization	Ribosome Disassembly Mitochondrial Translational Initiation
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Mitochondrial translation initiation
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aluminium levels ( 26025379) Daytime sleep phenotypes ( 27126917) Liver enzyme levels (aspartate transaminase) ( 24124411) Machado-Joseph disease (age at onset) ( 32205469) Multiple system atrophy ( 27629089) Non-albumin protein levels ( 29403010) Non-small cell lung cancer ( 23144319) Pancreatic cancer ( 20686608) Problematic alcohol use ( 32451486) Prudent dietary pattern ( 28644415) Regular attendance at a gym or sports club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 30224653) Tooth agenesis (third molar) ( 24172245) Urinary albumin-to-creatinine ratio ( 26631737) Weight ( 28552196)	Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)
Interacting Genes		25 interacting genes: AQP6 ARL13B CISD2 DARS2 FAM209A FKBP7 GJA8 GPR101 GPR152 GPR37L1 KCNJ6 KIR3DL1 LYVE1 MFSD14B MTIF3 PEX12 PIGP PLEKHO1 RANBP10 SLC14A1 SLC30A8 SPACA1 STOM SYT2 TMX2	85 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAN3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202
Entrez ID		80731	219402
HPRD ID		19009	17609
Ensembl ID		ENSG00000144229	ENSG00000122033
Uniprot IDs		Q9C0I4	Q9H2K0
PDB IDs			6NEQ 6NF8 6RW4 6RW5
Enriched GO Terms of Interacting Partners?
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