THSD7B and SLC14A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		THSD7B	SLC14A1
Description		thrombospondin type 1 domain containing 7B	solute carrier family 14 member 1 (Kidd blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function		Water Transmembrane Transporter Activity Urea Transmembrane Transporter Activity Urea Channel Activity
	Biological Process	Actin Cytoskeleton Reorganization	Water Transport Urea Transport Transmembrane Transport Urea Transmembrane Transport
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Transport of bile salts and organic acids, metal ions and amine compounds
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aluminium levels ( 26025379) Daytime sleep phenotypes ( 27126917) Liver enzyme levels (aspartate transaminase) ( 24124411) Machado-Joseph disease (age at onset) ( 32205469) Multiple system atrophy ( 27629089) Non-albumin protein levels ( 29403010) Non-small cell lung cancer ( 23144319) Pancreatic cancer ( 20686608) Problematic alcohol use ( 32451486) Prudent dietary pattern ( 28644415) Regular attendance at a gym or sports club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 30224653) Tooth agenesis (third molar) ( 24172245) Urinary albumin-to-creatinine ratio ( 26631737) Weight ( 28552196)	Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)
Interacting Genes		25 interacting genes: AQP6 ARL13B CISD2 DARS2 FAM209A FKBP7 GJA8 GPR101 GPR152 GPR37L1 KCNJ6 KIR3DL1 LYVE1 MFSD14B MTIF3 PEX12 PIGP PLEKHO1 RANBP10 SLC14A1 SLC30A8 SPACA1 STOM SYT2 TMX2	11 interacting genes: BTN2A2 C1GALT1 FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE
Entrez ID		80731	6563
HPRD ID		19009	00195
Ensembl ID		ENSG00000144229	ENSG00000141469
Uniprot IDs		Q9C0I4	B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336
PDB IDs			6QD5
Enriched GO Terms of Interacting Partners?
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