NUMBL and GPATCH8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NUMBL	GPATCH8
Description		NUMB like endocytic adaptor protein	G-patch domain containing 8
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cellular_component Nucleus
	Molecular Function	Protein Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Nervous System Development Axonogenesis Cytokine-mediated Signaling Pathway Protein Metabolic Process Lateral Ventricle Development Neuroblast Division In Subventricular Zone Adherens Junction Organization Positive Regulation Of Neurogenesis	Biological_process
Pathways
Drugs
Diseases
GWAS		Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Kawasaki disease ( 22446962) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730)	Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30578418)
Interacting Genes		24 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 UBE3A YWHAG	6 interacting genes: APH1A ATXN1 ATXN1L NUMBL RNPS1 SUMO2
Entrez ID		9253	23131
HPRD ID		04931	11089
Ensembl ID		ENSG00000105245	ENSG00000186566
Uniprot IDs		A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0	Q9UKJ3
PDB IDs		3F0W
Enriched GO Terms of Interacting Partners?
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