LRRFIP1 and FLII

Number of citations of the paper that reports this interaction (PubMedID 9671805)
17

Data Source:
HPRD (in vitro)

		LRRFIP1	FLII
Description		LRR binding FLII interacting protein 1	FLII actin remodeling protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded RNA Binding Protein Binding Protein Homodimerization Activity Cadherin Binding	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Actin Polymerization Or Depolymerization Myofibril Assembly Actin Filament Severing Barbed-end Actin Filament Capping
Pathways		Signaling by cytosolic FGFR1 fusion mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Adiposity ( 23505185) Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Longevity ( 30294719)
Interacting Genes		7 interacting genes: AP2B1 CEP44 FBXO7 FLII MED4 SERPINB5 SH2D2A	14 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MAPK7 MYD88 NCOA2 OPTN PRMT1 TRAIP
Entrez ID		9208	2314
HPRD ID		04460	02647
Ensembl ID		ENSG00000124831	ENSG00000177731
Uniprot IDs		A0A0F7NGI8 B4DPC0 Q32MZ4	Q13045
PDB IDs		4H22
Enriched GO Terms of Interacting Partners?
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