FLII and TRAIP

Number of citations of the paper that reports this interaction (PubMedID 9671805)
17

Data Source:
HPRD (in vitro, two hybrid)

		FLII	TRAIP
Description		FLII actin remodeling protein	TRAF interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite	Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm Site Of DNA Damage
	Molecular Function	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Actin Polymerization Or Depolymerization Myofibril Assembly Actin Filament Severing Barbed-end Actin Filament Capping	Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Replication Fork Processing Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production Protein-DNA Covalent Cross-linking Repair
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Blood protein levels ( 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Fasting insulin ( 34059833) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Multisite chronic pain ( 33830993) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077) Walking pace ( 33128006)
Interacting Genes		14 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MAPK7 MYD88 NCOA2 OPTN PRMT1 TRAIP	28 interacting genes: ALOX15B APP CEP19 CYLD FLII LXN MAGEF1 MAPRE2 MAPRE3 POLK POLR1C RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2
Entrez ID		2314	10293
HPRD ID		02647	05811
Ensembl ID		ENSG00000177731	ENSG00000183763
Uniprot IDs		Q13045	Q9BWF2
PDB IDs			4ZTD
Enriched GO Terms of Interacting Partners?
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