RFT1 and BEST2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RFT1	BEST2
Description		RFT1 homolog	bestrophin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Cilium Chloride Channel Complex
	Molecular Function	Protein Binding Glycolipid Floppase Activity	Molecular_function Chloride Channel Activity Protein Binding
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Transport Glycolipid Translocation	Chloride Transport Sensory Perception Of Smell Biological_process Membrane Depolarization
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective RFT1 causes RFT1-CDG (CDG-1n)	Stimuli-sensing channels
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Body shape index ( 34021172) Crohn's disease ( 28067908) Diastolic blood pressure ( 32902719) Feeling worry ( 29500382) Height ( 23563607 31562340) High density lipoprotein cholesterol levels ( 31928498) Hip circumference adjusted for BMI ( 34021172 25673412) Immune reponse to smallpox (secreted IL-2) ( 22610502) Schizophrenia ( 23974872) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: AQP6 BEST2 CNR2 CREB3L1 ERGIC3 MUC1 NEDD4 PSMA3 RNF144A TMX2 TNS2 TSPAN12	16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL MFSD5 PNLIPRP1 RFT1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B
Entrez ID		91869	54831
HPRD ID		15239	09548
Ensembl ID		ENSG00000163933	ENSG00000039987
Uniprot IDs		Q96AA3	Q8NFU1
PDB IDs
Enriched GO Terms of Interacting Partners?
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