RFT1 and TSPAN12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RFT1	TSPAN12
Description		RFT1 homolog	tetraspanin 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Glycolipid Floppase Activity	Protein Binding Wnt-activated Receptor Activity
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Transport Glycolipid Translocation	Angiogenesis Cell Surface Receptor Signaling Pathway Retina Layer Formation Regulation Of Angiogenesis Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective RFT1 causes RFT1-CDG (CDG-1n)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Body shape index ( 34021172) Crohn's disease ( 28067908) Diastolic blood pressure ( 32902719) Feeling worry ( 29500382) Height ( 23563607 31562340) High density lipoprotein cholesterol levels ( 31928498) Hip circumference adjusted for BMI ( 34021172 25673412) Immune reponse to smallpox (secreted IL-2) ( 22610502) Schizophrenia ( 23974872) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Bitter alcoholic beverage consumption ( 31046077) Heel bone mineral density ( 30598549)
Interacting Genes		12 interacting genes: AQP6 BEST2 CNR2 CREB3L1 ERGIC3 MUC1 NEDD4 PSMA3 RNF144A TMX2 TNS2 TSPAN12	21 interacting genes: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218
Entrez ID		91869	23554
HPRD ID		15239	15509
Ensembl ID		ENSG00000163933	ENSG00000106025
Uniprot IDs		Q96AA3	A0A024R740 O95859
PDB IDs
Enriched GO Terms of Interacting Partners?
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