BEST2 and UNC93B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BEST2	UNC93B1
Description		bestrophin 2	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Chloride Channel Complex	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	Molecular_function Chloride Channel Activity Protein Binding	Protein Binding Toll-like Receptor Binding
	Biological Process	Chloride Transport Sensory Perception Of Smell Biological_process Membrane Depolarization	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Stimuli-sensing channels	Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS			Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL MFSD5 PNLIPRP1 RFT1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B	27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237
Entrez ID		54831	81622
HPRD ID		09548	12191
Ensembl ID		ENSG00000039987	ENSG00000110057
Uniprot IDs		Q8NFU1	Q9H1C4
PDB IDs			7C76 7CYN
Enriched GO Terms of Interacting Partners?
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