ACBD5 and GRM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ACBD5	GRM2
Description		acyl-CoA binding domain containing 5	glutamate metabotropic receptor 2
Image
GO Annotations	Cellular Component	Nucleoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Presynaptic Membrane Astrocyte Projection Integral Component Of Postsynaptic Membrane
	Molecular Function	Fatty-acyl-CoA Binding Molecular_function Lipid Binding	Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity Group II Metabotropic Glutamate Receptor Activity G Protein-coupled Receptor Activity Calcium Channel Regulator Activity Protein Binding Glutamate Receptor Activity Scaffold Protein Binding
	Biological Process	Macroautophagy Autophagy Of Peroxisome Aggrephagy	Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Gene Expression Glutamate Secretion Regulation Of Glutamate Secretion Regulation Of Dopamine Secretion Behavioral Response To Nicotine Response To Cocaine Regulation Of Protein Kinase B Signaling Regulation Of Synaptic Transmission, Glutamatergic Glutamate Homeostasis Regulation Of Response To Drug
Pathways		Peroxisomal lipid metabolism RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs			LY2140023
Diseases
GWAS
Interacting Genes		5 interacting genes: GPR158 GRM2 SLC38A7 STX1B TMEM229B	29 interacting genes: ACBD5 AQP6 BIK CCDC107 CLDN2 CLDN9 CPLX4 CYB5R3 GNA15 GNAQ GRIP1 LMNA MFSD14B MGST3 MMGT1 NAALADL2 PDZK1IP1 RGS12 SAR1A SDCBP SLC30A8 SLC38A1 STOM TAMALIN TMEM130 TMEM237 TMEM248 TSPAN18 UBQLN1
Entrez ID		91452	2912
HPRD ID		12415	04977
Ensembl ID		ENSG00000107897	ENSG00000164082
Uniprot IDs		B7Z2A7 B7Z2R7 B7Z9D0 Q5T8D3 Q8NCM9	Q14416
PDB IDs		3FLV	4XAQ 4XAS 5CNI 5CNJ 5KZN 5KZQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?