GRM2 and ACBD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GRM2	ACBD5
Description		glutamate metabotropic receptor 2	acyl-CoA binding domain containing 5
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Presynaptic Membrane Astrocyte Projection Integral Component Of Postsynaptic Membrane	Nucleoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity Group II Metabotropic Glutamate Receptor Activity G Protein-coupled Receptor Activity Calcium Channel Regulator Activity Protein Binding Glutamate Receptor Activity Scaffold Protein Binding	Fatty-acyl-CoA Binding Molecular_function Lipid Binding
	Biological Process	Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Gene Expression Glutamate Secretion Regulation Of Glutamate Secretion Regulation Of Dopamine Secretion Behavioral Response To Nicotine Response To Cocaine Regulation Of Protein Kinase B Signaling Regulation Of Synaptic Transmission, Glutamatergic Glutamate Homeostasis Regulation Of Response To Drug	Macroautophagy Autophagy Of Peroxisome Aggrephagy
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	Peroxisomal lipid metabolism RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import
Drugs		LY2140023
Diseases
GWAS
Interacting Genes		29 interacting genes: ACBD5 AQP6 BIK CCDC107 CLDN2 CLDN9 CPLX4 CYB5R3 GNA15 GNAQ GRIP1 LMNA MFSD14B MGST3 MMGT1 NAALADL2 PDZK1IP1 RGS12 SAR1A SDCBP SLC30A8 SLC38A1 STOM TAMALIN TMEM130 TMEM237 TMEM248 TSPAN18 UBQLN1	5 interacting genes: GPR158 GRM2 SLC38A7 STX1B TMEM229B
Entrez ID		2912	91452
HPRD ID		04977	12415
Ensembl ID		ENSG00000164082	ENSG00000107897
Uniprot IDs		Q14416	B7Z2A7 B7Z2R7 B7Z9D0 Q5T8D3 Q8NCM9
PDB IDs		4XAQ 4XAS 5CNI 5CNJ 5KZN 5KZQ	3FLV
Enriched GO Terms of Interacting Partners?
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