AIFM1 and DCAF7

		AIFM1	DCAF7
Description		apoptosis inducing factor mitochondria associated 1	DDB1 and CUL4 associated factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	DNA Binding NADH Dehydrogenase Activity Protein Binding NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Response To Ischemia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Toxic Substance Programmed Cell Death Chromosome Condensation Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Protein Import Into Mitochondrial Intermembrane Space Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hydrogen Peroxide Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Cellular Response To Oxygen-glucose Deprivation Response To L-glutamate Regulation Of Apoptotic DNA Fragmentation Cellular Response To Aldosterone	Protein Ubiquitination
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs		Flavin adenine dinucleotide MCC
Diseases
GWAS		Bipolar disorder ( 31043756)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: CASP3 DCAF7 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP	17 interacting genes: ACE AIFM1 APP ATP13A2 ATP5PD BMPR1B CBX1 DYRK1B LIG1 PCTP PWP2 SPDYA TANC2 TK1 TLK2 YWHAB YWHAG
Entrez ID		9131	10238
HPRD ID		02161	09340
Ensembl ID		ENSG00000156709	ENSG00000136485
Uniprot IDs		E9PMA0 O95831	P61962
PDB IDs		1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI
Enriched GO Terms of Interacting Partners?
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