DCAF7 and CBX1

		DCAF7	CBX1
Description		DDB1 and CUL4 associated factor 7	chromobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Protein Ubiquitination	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation	HCMV Early Events
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Aspartate aminotransferase levels ( 33547301) Body mass index ( 26426971 20935630) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Generalized epilepsy ( 22949513)
Interacting Genes		17 interacting genes: ACE AIFM1 APP ATP13A2 ATP5PD BMPR1B CBX1 DYRK1B LIG1 PCTP PWP2 SPDYA TANC2 TK1 TLK2 YWHAB YWHAG	37 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID		10238	10951
HPRD ID		09340	05149
Ensembl ID		ENSG00000136485	ENSG00000108468
Uniprot IDs		P61962	P83916 Q6IBN6
PDB IDs			2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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