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NMI and CNOT7
Number of citations of the paper that reports this interaction (PubMedID
30217970
)
5
Data Source:
BioGRID
(two hybrid)
NMI
CNOT7
Description
N-myc and STAT interactor
CCR4-NOT transcription complex subunit 7
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
P-body
Nucleus
Cytoplasm
Cytosol
Membrane
Nuclear Body
Nuclear Speck
CCR4-NOT Complex
CCR4-NOT Core Complex
Molecular Function
Transcription Coregulator Activity
Protein Binding
Identical Protein Binding
3'-5'-exoribonuclease Activity
Transcription Corepressor Activity
RNA Binding
Exoribonuclease Activity
Poly(A)-specific Ribonuclease Activity
Protein Binding
Metal Ion Binding
DNA-binding Transcription Factor Binding
Biological Process
Macrophage Activation Involved In Immune Response
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cell Population Proliferation
Response To Virus
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Positive Regulation Of Inflammatory Response
Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein K48-linked Ubiquitination
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Gene Silencing By RNA
P-body Assembly
Gene Silencing By MiRNA
Regulation Of Tyrosine Phosphorylation Of STAT Protein
Exonucleolytic Catabolism Of Deadenylated MRNA
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Virus
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Positive Regulation Of MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Interacting Genes
60 interacting genes:
BRAT1
BRCA1
BRMS1
C1orf216
C9orf72
CDKN2A
CDKN2D
CNKSR3
CNOT7
COPS7B
CYP2E1
EMILIN1
EPC2
EXOSC5
GART
GCSH
GOLGA8EP
HDDC3
HGS
HHLA3
HOXC9
HSPA8
HSPH1
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MCPH1
MORF4L1
MTMR6
MTMR9
MYC
MYCN
MYOM3
NECAP2
POMZP3
PSMA1
RYBP
SCEL
SFR1
SH3GLB2
SINHCAF
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
THAP8
TRAF5
TRIM72
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
UBE2I
29 interacting genes:
ALMS1
APP
BTG1
BTG2
BTG3
CDK1
CDK2
CDK4
CDK6
CNOT6
FBXO7
FHL3
FOXC2
HOXD4
IKBKG
LSM3
MRFAP1L1
NMI
PABPC1
PIAS1
PSMC1
PSMC2
SCARA3
SH3GLB2
TCP11L1
TEX11
TOB1
TOB2
TSG101
Entrez ID
9111
29883
HPRD ID
04632
05370
Ensembl ID
ENSG00000123609
ENSG00000198791
Uniprot IDs
Q13287
Q96IQ6
Q9UIV1
PDB IDs
2D5R
4GMJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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