NMI and COPS7B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		NMI	COPS7B
Description		N-myc and STAT interactor	COP9 signalosome subunit 7B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Nucleoplasm Cytosol COP9 Signalosome
	Molecular Function	Transcription Coregulator Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Interferon-gamma-mediated Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein K48-linked Ubiquitination	Protein Deneddylation COP9 Signalosome Assembly
Pathways			DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Height ( 18391951)
Interacting Genes		60 interacting genes: BRAT1 BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EPC2 EXOSC5 GART GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I	11 interacting genes: APP BEX5 COPS2 COPS3 COPS4 COPS5 COPS6 EIF3E GPS1 NMI PMF1
Entrez ID		9111	64708
HPRD ID		04632	09889
Ensembl ID		ENSG00000123609	ENSG00000144524
Uniprot IDs		Q13287	A0A024R471 A0A024R478 A0A087X1P5 J3KQ34 J3KQ41 Q6ZTQ7 Q9H9Q2
PDB IDs			6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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