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CNOT7 and MRFAP1L1
Number of citations of the paper that reports this interaction (PubMedID
30217970
)
5
Data Source:
BioGRID
(two hybrid)
CNOT7
MRFAP1L1
Description
CCR4-NOT transcription complex subunit 7
Morf4 family associated protein 1 like 1
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
Membrane
Nuclear Body
Nuclear Speck
CCR4-NOT Complex
CCR4-NOT Core Complex
Molecular Function
3'-5'-exoribonuclease Activity
Transcription Corepressor Activity
RNA Binding
Exoribonuclease Activity
Poly(A)-specific Ribonuclease Activity
Protein Binding
Metal Ion Binding
DNA-binding Transcription Factor Binding
Protein Binding
Identical Protein Binding
Biological Process
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Gene Silencing By RNA
P-body Assembly
Gene Silencing By MiRNA
Regulation Of Tyrosine Phosphorylation Of STAT Protein
Exonucleolytic Catabolism Of Deadenylated MRNA
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Virus
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Positive Regulation Of MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Interacting Genes
29 interacting genes:
ALMS1
APP
BTG1
BTG2
BTG3
CDK1
CDK2
CDK4
CDK6
CNOT6
FBXO7
FHL3
FOXC2
HOXD4
IKBKG
LSM3
MRFAP1L1
NMI
PABPC1
PIAS1
PSMC1
PSMC2
SCARA3
SH3GLB2
TCP11L1
TEX11
TOB1
TOB2
TSG101
47 interacting genes:
ABI1
ABI2
ABI3
BYSL
C1orf216
C3orf62
CAGE1
CAVIN3
CDK2AP1
CDK2AP2
CENPK
CEP44
CNOT7
CSPP1
EIF2B2
GAS8
GTF2IRD1
HGS
HTT
IHO1
JAKMIP1
LMO2
LNX1
LNX2
MEOX2
MORF4L1
MORF4L2
MRFAP1
NTAQ1
PIH1D2
PIK3R2
PSMA1
RADIL
RDM1
SDCBP
SFR1
SMARCE1
SMU1
SYCE1
TCF4
TEX11
TMEM126B
TSNAX
TXN2
UBTD1
ZDHHC17
ZNF417
Entrez ID
29883
114932
HPRD ID
05370
15162
Ensembl ID
ENSG00000198791
ENSG00000178988
Uniprot IDs
Q96IQ6
Q9UIV1
A0A075DDR2
Q96HT8
PDB IDs
2D5R
4GMJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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