CD1B and PSAP

Number of citations of the paper that reports this interaction (PubMedID 14716313)
61

Data Source:
HPRD (in vitro)

		CD1B	PSAP
Description		CD1b molecule	prosaposin
Image
GO Annotations	Cellular Component	Extracellular Space Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Azurophil Granule Membrane Lysosomal Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding	Protease Binding Protein Binding Phospholipid Binding Enzyme Activator Activity Protein Homodimerization Activity Scaffold Protein Binding Ganglioside GM1 Binding Ganglioside GM2 Binding Ganglioside GM3 Binding Ganglioside GT1b Binding Ganglioside GP1c Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib	Sphingolipid Metabolic Process Lysosomal Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Autophagy Regulation Of Lipid Metabolic Process Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Positive Regulation Of Beta-galactosidase Activity Ganglioside GM1 Transport To Membrane
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Platelet degranulation Glycosphingolipid metabolism Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation
Drugs			Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
GWAS			Asthma (childhood onset) ( 23829686) Seasonality and depression ( 30217971)
Interacting Genes		3 interacting genes: B2M HSBP1 PSAP	21 interacting genes: APPBP2 BACE1 BRCA1 CD1B CELSR1 COPS6 CPEB2 CTSD ERBB2 GBA MAFF NLGN3 PEX5 PRAG1 SGCG SMAD2 SMAD9 TOMM70 UBE3A USP4 ZBED1
Entrez ID		910	5660
HPRD ID		01775	01460
Ensembl ID		ENSG00000158485	ENSG00000197746
Uniprot IDs		P29016	A0A024QZQ2 P07602
PDB IDs		1GZP 1GZQ 1UQS 2H26 3OV6 3T8X 4ONO 5C9J 5L2J 5L2K 5WKE 5WKG 5WKI 5WL1 6CUG 6D64	1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ 4UEX 4V2O 6SLR
Enriched GO Terms of Interacting Partners?
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