PSAP and CD1B

Number of citations of the paper that reports this interaction (PubMedID 14716313)
61

Data Source:
HPRD (in vitro)

		PSAP	CD1B
Description		prosaposin	CD1b molecule
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Azurophil Granule Membrane Lysosomal Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Space Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protease Binding Protein Binding Phospholipid Binding Enzyme Activator Activity Protein Homodimerization Activity Scaffold Protein Binding Ganglioside GM1 Binding Ganglioside GM2 Binding Ganglioside GM3 Binding Ganglioside GT1b Binding Ganglioside GP1c Binding	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Sphingolipid Metabolic Process Lysosomal Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Autophagy Regulation Of Lipid Metabolic Process Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Positive Regulation Of Beta-galactosidase Activity Ganglioside GM1 Transport To Membrane	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Platelet degranulation Glycosphingolipid metabolism Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
GWAS		Asthma (childhood onset) ( 23829686) Seasonality and depression ( 30217971)
Interacting Genes		21 interacting genes: APPBP2 BACE1 BRCA1 CD1B CELSR1 COPS6 CPEB2 CTSD ERBB2 GBA MAFF NLGN3 PEX5 PRAG1 SGCG SMAD2 SMAD9 TOMM70 UBE3A USP4 ZBED1	3 interacting genes: B2M HSBP1 PSAP
Entrez ID		5660	910
HPRD ID		01460	01775
Ensembl ID		ENSG00000197746	ENSG00000158485
Uniprot IDs		A0A024QZQ2 P07602	P29016
PDB IDs		1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ 4UEX 4V2O 6SLR	1GZP 1GZQ 1UQS 2H26 3OV6 3T8X 4ONO 5C9J 5L2J 5L2K 5WKE 5WKG 5WKI 5WL1 6CUG 6D64
Enriched GO Terms of Interacting Partners?
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