ZNF598 and CDA

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ZNF598	CDA
Description		zinc finger protein 598, E3 ubiquitin ligase	cytidine deaminase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Protein Binding Ribosome Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Deoxycytidine Deaminase Activity
	Biological Process	Protein Monoubiquitination Protein Ubiquitination Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Negative Regulation Of Nucleotide Metabolic Process
Pathways			Neutrophil degranulation Pyrimidine salvage
Drugs			1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		5 interacting genes: CDA CXCL8 DBN1 GLIS2 UBE2D1	18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598
Entrez ID		90850	978
HPRD ID		11732	11744
Ensembl ID		ENSG00000167962	ENSG00000158825
Uniprot IDs		Q86UK7	P32320
PDB IDs			1MQ0
Enriched GO Terms of Interacting Partners?
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