CDA and ADAT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDA	ADAT3
Description		cytidine deaminase	adenosine deaminase tRNA specific 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Nucleoplasm
	Molecular Function	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Deoxycytidine Deaminase Activity	Protein Binding Metal Ion Binding TRNA-specific Adenosine-34 Deaminase Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Negative Regulation Of Nucleotide Metabolic Process	TRNA Processing
Pathways		Neutrophil degranulation Pyrimidine salvage	tRNA modification in the nucleus and cytosol
Drugs		1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598	5 interacting genes: CDA FBLIM1 REEP6 SORBS3 THRB
Entrez ID		978	113179
HPRD ID		11744	14000
Ensembl ID		ENSG00000158825	ENSG00000213638
Uniprot IDs		P32320	D6W601 Q96EY9
PDB IDs		1MQ0
Enriched GO Terms of Interacting Partners?
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