CDA and FOXN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDA	FOXN1
Description		cytidine deaminase	forkhead box N1
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Chromatin Nucleus
	Molecular Function	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Deoxycytidine Deaminase Activity	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Negative Regulation Of Nucleotide Metabolic Process	Hair Follicle Development T Cell Lineage Commitment Regulation Of Transcription By RNA Polymerase II Defense Response Epidermis Development Animal Organ Morphogenesis Keratinocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Nail Development T Cell Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Positive Regulation Of Hair Follicle Development Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Regulation Of Positive Thymic T Cell Selection
Pathways		Neutrophil degranulation Pyrimidine salvage
Drugs		1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995)	Bone mineral density ( 31790847) Metabolite levels ( 31628463) Tonsillectomy ( 27182965 28928442)
Interacting Genes		18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598	12 interacting genes: CDA CDC23 DMRT3 HOXA1 LHX8 MAPKBP1 PIN1 SPATC1L TLE5 TRAF2 TRAPPC6A TSSK1B
Entrez ID		978	8456
HPRD ID		11744	02907
Ensembl ID		ENSG00000158825	ENSG00000109101
Uniprot IDs		P32320	O15353
PDB IDs		1MQ0	5OCN 6EL8
Enriched GO Terms of Interacting Partners?
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