LDB2 and EPM2AIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LDB2	EPM2AIP1
Description		LIM domain binding 2	EPM2A interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Plasma Membrane Cell Leading Edge	Nucleus Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Nervous System Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription By RNA Polymerase II	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Liver fibrosis (total hepatic collagen content) ( 32953199) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)	Autism spectrum disorder or schizophrenia ( 28540026) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Subjective response to lithium treatment ( 26503763) Triglyceride levels ( 32203549)
Interacting Genes		29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19	46 interacting genes: ACTN1 APPL2 ARHGEF5 C1orf50 CBFA2T3 CCNB1IP1 CNTROB CPSF7 DTX3 EMP2 EPM2A FHL3 GFAP HSF2BP KCTD1 KCTD9 KRT16 KRT75 LDB2 LIN52 LNX1 MAD2L1 MEOX2 MX1 NOC4L OTUD7B PICK1 PRTFDC1 PSMA7 RBMY1F RBMY1J REL SERPINF1 SWSAP1 TFIP11 TNFAIP1 TNKS TRA2B TRIM50 TRIM54 USP54 VPS52 ZBTB14 ZIM2 ZNF620 ZSCAN18
Entrez ID		9079	9852
HPRD ID		16022	07445
Ensembl ID		ENSG00000169744	ENSG00000178567
Uniprot IDs		B7Z6D0 E9PFI4 G5E9Y7 O43679	Q7L775
PDB IDs
Enriched GO Terms of Interacting Partners?
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