LDB2 and LHX9

Number of citations of the paper that reports this interaction (PubMedID 9880598)
44

Data Source:
HPRD (in vitro)

		LDB2	LHX9
Description		LIM domain binding 2	LIM homeobox 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Plasma Membrane Cell Leading Edge	Chromatin Nucleus
	Molecular Function	Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Nervous System Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Dorsal Spinal Cord Interneuron Anterior Axon Guidance
Pathways			Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Liver fibrosis (total hepatic collagen content) ( 32953199) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)	General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)
Interacting Genes		29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19	9 interacting genes: CSNK2A1 CWF19L2 IGFN1 KHK LDB1 LDB2 SMAD2 SMURF1 UBTFL1
Entrez ID		9079	56956
HPRD ID		16022	07299
Ensembl ID		ENSG00000169744	ENSG00000143355
Uniprot IDs		B7Z6D0 E9PFI4 G5E9Y7 O43679	H0YL54 Q9NQ69
PDB IDs			2DMQ
Enriched GO Terms of Interacting Partners?
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