USP13 and SPRR2C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	SPRR2C
Description		ubiquitin specific peptidase 13	small proline rich protein 2C (pseudogene)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS			Asthma ( 31619474)
Interacting Genes		24 interacting genes: AMFR BAG6 CLK3 DAZAP2 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	1 interacting genes: USP13
Entrez ID		8975	6702
HPRD ID		04666	01651
Ensembl ID		ENSG00000058056
Uniprot IDs		A0A0A6YZ17 Q92995
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?
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