USP13 and MYO15A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	MYO15A
Description		ubiquitin specific peptidase 13	myosin XVA
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	Microfilament Motor Activity Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Actin Filament Organization Sensory Perception Of Sound Locomotory Behavior Vesicle Transport Along Actin Filament Inner Ear Morphogenesis
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS			Basal cell carcinoma ( 33549134) Change in neurofilament light levels ( 31295725) Haemorrhoidal disease ( 33888516) Hip index ( 34021172) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Schizophrenia ( 25056061) Serum folate levels ( 29953918) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		24 interacting genes: AMFR BAG6 CLK3 DAZAP2 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	4 interacting genes: EPS8 FASLG USP13 WHRN
Entrez ID		8975	51168
HPRD ID		04666	04049
Ensembl ID		ENSG00000058056	ENSG00000091536
Uniprot IDs		A0A0A6YZ17 Q92995	Q9UKN7
PDB IDs		2L80 2LBC	6KZ1
Enriched GO Terms of Interacting Partners?
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