PHOX2B and PTGFR

		PHOX2B	PTGFR
Description		paired like homeobox 2B	prostaglandin F receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	Prostaglandin F Receptor Activity
	Biological Process	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Nervous System Process Noradrenergic Neuron Differentiation Noradrenergic Neuron Development Brainstem Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Glial Cell Differentiation Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation In Hindbrain Medullary Reticular Formation Development Hindbrain Tangential Cell Migration Skeletal Muscle Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Autonomic Nervous System Development Enteric Nervous System Development Sympathetic Nervous System Development Parasympathetic Nervous System Development Inner Ear Development Efferent Axon Development In A Lateral Line Nerve Regulation Of Cell Cycle Respiratory System Development Retrotrapezoid Nucleus Neuron Differentiation Sympathetic Ganglion Development Dopaminergic Neuron Differentiation Cellular Response To BMP Stimulus Positive Regulation Of Cold-induced Thermogenesis Neural Crest Cell Migration Involved In Autonomic Nervous System Development	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways			Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS		Bone mineral density (femoral neck) ( 26911590) Hirschsprung disease ( 27702942)	Bipolar disorder ( 22182935) Depression in multiple sclerosis (post-diagnosis) ( 33296963) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		1 interacting genes: PTGFR	12 interacting genes: AGTR1 CTH FPGT GTPBP4 IKBKE NOC2L PHOX2B PTGDS PTGER1 PTGER2 PTGES2 PTPRT
Entrez ID		8929	5737
HPRD ID		09157	08988
Ensembl ID		ENSG00000109132	ENSG00000122420
Uniprot IDs		Q99453	P43088
PDB IDs
Enriched GO Terms of Interacting Partners?
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