CCNC and MBIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CCNC	MBIP
Description		cyclin C	MAP3K12 binding inhibitory protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Identical Protein Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Catalytic Activity	Positive Regulation Of Gene Expression Negative Regulation Of Catalytic Activity Histone H3 Acetylation Positive Regulation Of JNK Cascade
Pathways		PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	HATs acetylate histones
Drugs
Diseases
GWAS		Daytime nap ( 33568662) Erectile dysfunction ( 30297428) Refractive error ( 32231278)	Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)
Interacting Genes		80 interacting genes: ASH2L BLOC1S2 BTBD2 CCHCR1 CCNH CDK3 CDK8 CDKN2B CFAP53 CKS1B CRX DYDC1 ERCC3 ESR2 FAM161A FAM50B FAM90A1 FOXP2 FOXR2 GADD45GIP1 GLYR1 GOLGA2 GPC4 HSPB1 ISY1 KRT13 KRT15 KRT16 KRT27 KRT31 KRT34 LCN2 LZTS2 MBD3 MBIP MCM2 MED8 MEOX2 MGST3 MYO15B NDUFB7 NDUFV2 NEFL NMNAT1 NRBF2 PAX5 PBXIP1 PLEKHO2 PLIN3 PNMA5 POU6F2 PRPF18 PUF60 RB1 RBM41 REL RFC5 RIBC1 RPA2 RUSC1 SERTAD3 SHC3 SPAG8 TADA3 TCEANC TEPSIN TEX12 TP63 TRAF3IP3 TRIM39 TRIM54 UBE2K VHL VTA1 ZFP90 ZNF18 ZNF426 ZNF620 ZNF688 ZNF792	47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		892	51562
HPRD ID		00456	14368
Ensembl ID		ENSG00000112237	ENSG00000151332
Uniprot IDs		P24863 Q7Z4L3	B2RCV0 Q9NS73
PDB IDs		3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2 6QTG 6QTJ 6R3S 6T41 6TPA 6Y0A
Enriched GO Terms of Interacting Partners?
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