MBIP and MOAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MBIP	MOAP1
Description		MAP3K12 binding inhibitory protein 1	modulator of apoptosis 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Positive Regulation Of Gene Expression Negative Regulation Of Catalytic Activity Histone H3 Acetylation Positive Regulation Of JNK Cascade	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)	Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)
Interacting Genes		47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5	24 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FXR1 FZR1 LATS1 MAGEH1 MBIP MEOX2 PNMA5 PPP2R3C RASSF1 RUSC1 THOC1 TNFRSF10A TNFRSF1A UBQLN2 UBQLN4 UBR5 ZMYND12
Entrez ID		51562	64112
HPRD ID		14368	17580
Ensembl ID		ENSG00000151332	ENSG00000165943
Uniprot IDs		B2RCV0 Q9NS73	Q96BY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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