SQSTM1 and SLIT3

SQSTM1

SLIT3

Description sequestosome 1 slit guidance ligand 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 24162737)
  • Monocyte percentage of white cells ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • Atrial fibrillation ( 30061737)
  • Bipolar disorder x sex interaction ( 34099189)
  • Body mass index ( 31217584)
  • Circulating leptin levels in high cardiovascular risk ( 31766143)
  • Circulating leptin levels x sex interaction in high cardiovascular risk ( 31766143)
  • Diastolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009)
  • Gut microbiota (functional units) ( 27694959)
  • Hallux valgus ( 32131869)
  • Height ( 28552196 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory skin disease ( 25574825)
  • Menarche (age at onset) ( 25231870)
  • Non-word reading ( 30741946)
  • Total cholesterol levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Treatment resistant depression ( 30468137)
Interacting Genes 108 interacting genes: ATXN3 BCL2 BMPR1B BPTF BRCA1 CALCR CALM1 CALR CAMK2A CCNB1 CDC37 CDC6 CDK1 CRBN CRYAB CSNK1A1 CSNK2A1 DAXX DAZAP2 DNAI1 DNAI2 DNAJC10 EEF1D FKBP4 GABARAP GABARAPL1 GABARAPL2 GABRR1 GABRR2 GEMIN4 GRB14 GRIA1 GRIA2 GRIA3 HSPA5 HSPB1 IKBKB IRAK1 KAT5 KCNAB2 KEAP1 LCK LINC01554 LRRK2 MALT1 MAP1LC3B MAP2K5 MAPK13 MAPK14 MAPT MBP MEIS2 MLH1 MTDH NBR1 NCOR1 NEDD4 NR2F2 NSD3 NTRK1 NTRK2 NTRK3 OGT PADI1 PAWR PIK3CA PIK3R1 PPHLN1 PRKCD PRKCI PRKCZ RAD23A RAD54L2 RELN RIPK1 RNF166 RNF168 RPL37 SKP2 SLIT3 SMAD1 SMAD2 SMAD3 SMAD4 SMURF1 SNCA STXBP1 TBK1 TGFBR1 TKT TOE1 TP53INP1 TRAF6 TRIB3 TRIM21 TRIM55 TRIM63 TTN UBA52 UBB UBE2D2 UBE2D3 ULK2 USP8 VANGL2 WDR81 XIAP YWHAZ 11 interacting genes: CAPN1 CASP9 HRH2 IGSF8 KHDRBS3 MAML1 MAPK9 MGAT4B ROBO2 RXRB SQSTM1
Entrez ID 8878 6586
HPRD ID 03319 04775
Ensembl ID ENSG00000161011 ENSG00000184347
Uniprot IDs Q13501 O75094
PDB IDs 1Q02 2JY7 2JY8 2K0B 2KNV 4MJS 4UF8 4UF9 5YP7 5YP8 5YPA 5YPB 5YPC 5YPE 5YPF 5YPG 5YPH 6JM4 6KHZ 6MJ7 6TGY 6TH3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?