SERPINH1 and PC

		SERPINH1	PC
Description		serpin family H member 1	pyruvate carboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Raft Collagen-containing Extracellular Matrix	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding	Pyruvate Carboxylase Activity Protein Binding ATP Binding Biotin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Pyruvate Metabolic Process Gluconeogenesis Lipid Metabolic Process Negative Regulation Of Gene Expression Viral RNA Genome Packaging Positive Regulation By Host Of Viral Release From Host Cell Positive Regulation By Host Of Viral Process
Pathways		Collagen biosynthesis and modifying enzymes	Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Gluconeogenesis
Drugs			Pyruvic acid Biotin 5-(hexahydro-2-oxo-1H-thieno[3,4-D]imidazol-6-yl)pentanal
Diseases
GWAS		Body shape index ( 34021172) Coronary artery disease ( 29212778 33020668) Height ( 28552196 20881960 22021425 25282103 25429064 31562340 28270201 33713608) Hip circumference adjusted for BMI ( 34021172 25673412) Myocardial infarction ( 33532862) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 28448500)	Bipolar disorder ( 21926972 31043756) Body shape index ( 34021172) Familial squamous cell lung carcinoma ( 29924316) Hip circumference adjusted for BMI ( 34021172) HIV-1 susceptibility ( 22174851) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		20 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KLF13 LINC01554 NSG2 OGT PC PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	6 interacting genes: GOT1 GOT2 MDH2 MYO7A PCBP2 SERPINH1
Entrez ID		871	5091
HPRD ID		02968	02032
Ensembl ID		ENSG00000149257	ENSG00000173599
Uniprot IDs		A0A024R5K8 A8K259 P50454	A0A024R5C5 P11498
PDB IDs			3BG3 3BG9
Enriched GO Terms of Interacting Partners?
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