PC and SERPINH1

		PC	SERPINH1
Description		pyruvate carboxylase	serpin family H member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Raft Collagen-containing Extracellular Matrix
	Molecular Function	Pyruvate Carboxylase Activity Protein Binding ATP Binding Biotin Binding Identical Protein Binding Metal Ion Binding	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding
	Biological Process	Pyruvate Metabolic Process Gluconeogenesis Lipid Metabolic Process Negative Regulation Of Gene Expression Viral RNA Genome Packaging Positive Regulation By Host Of Viral Release From Host Cell Positive Regulation By Host Of Viral Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Gluconeogenesis	Collagen biosynthesis and modifying enzymes
Drugs		Pyruvic acid Biotin 5-(hexahydro-2-oxo-1H-thieno[3,4-D]imidazol-6-yl)pentanal
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Body shape index ( 34021172) Familial squamous cell lung carcinoma ( 29924316) Hip circumference adjusted for BMI ( 34021172) HIV-1 susceptibility ( 22174851) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)	Body shape index ( 34021172) Coronary artery disease ( 29212778 33020668) Height ( 28552196 20881960 22021425 25282103 25429064 31562340 28270201 33713608) Hip circumference adjusted for BMI ( 34021172 25673412) Myocardial infarction ( 33532862) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 28448500)
Interacting Genes		6 interacting genes: GOT1 GOT2 MDH2 MYO7A PCBP2 SERPINH1	20 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KLF13 LINC01554 NSG2 OGT PC PPARG SLC2A4 SLC35F6 UBQLN4 UBTF
Entrez ID		5091	871
HPRD ID		02032	02968
Ensembl ID		ENSG00000173599	ENSG00000149257
Uniprot IDs		A0A024R5C5 P11498	A0A024R5K8 A8K259 P50454
PDB IDs		3BG3 3BG9
Enriched GO Terms of Interacting Partners?
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