EIF3D and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EIF3D	CCDC57
Description		eukaryotic translation initiation factor 3 subunit D	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Cytoplasm Centrosome Centriole Spindle Microtubule Centriolar Satellite
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding	Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: ANKRD28 BEND5 CCDC125 CCDC57 CDC42 CEP70 CREBBP DNAJB11 DVL3 EIF3G EIF3J EIF3L EIF5 ERCC6 GOLGA6L9 HOMER3 HOOK2 HSF2BP KIFC3 LZTS2 MORN3 MTUS2 OGT PHLDA1 PICK1 POLR2G REL SAT1 TFIP11 TRIM23 TRIM27 ZRANB1	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 C2CD6 C4orf45 C9orf24 CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PPP1R32 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		8664	284001
HPRD ID		04888	14150
Ensembl ID		ENSG00000100353	ENSG00000176155
Uniprot IDs		O15371	A0A590UJT6 Q2TAC2
PDB IDs		6YBD 6YBS 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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