EIF3D and BEND5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EIF3D	BEND5
Description		eukaryotic translation initiation factor 3 subunit D	BEN domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Golgi Apparatus
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding	DNA Binding Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding	Negative Regulation Of Transcription, DNA-templated
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		32 interacting genes: ANKRD28 BEND5 CCDC125 CCDC57 CDC42 CEP70 CREBBP DNAJB11 DVL3 EIF3G EIF3J EIF3L EIF5 ERCC6 GOLGA6L9 HOMER3 HOOK2 HSF2BP KIFC3 LZTS2 MORN3 MTUS2 OGT PHLDA1 PICK1 POLR2G REL SAT1 TFIP11 TRIM23 TRIM27 ZRANB1	30 interacting genes: APP BUD31 CTNNBIP1 DDR1 EIF3D ERBB3 FAM161A FXR1 GFI1B GORASP2 GRAP2 HOXA1 LCE1B LMO3 NTAQ1 PIMREG PRKAB2 PTGR2 RTP5 SMARCD1 TSC1 TSPOAP1 UBE2I USP2 USP20 USP7 VPS25 ZGPAT ZNF417 ZNF688
Entrez ID		8664	79656
HPRD ID		04888	07756
Ensembl ID		ENSG00000100353	ENSG00000162373
Uniprot IDs		O15371	A0A0S2Z5N0 Q7L4P6
PDB IDs		6YBD 6YBS 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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