CCDC57 and SMG9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC57	SMG9
Description		coiled-coil domain containing 57	SMG9 nonsense mediated mRNA decay factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Spindle Microtubule Centriolar Satellite	Cytosol
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Eye Development In Utero Embryonic Development Brain Development Heart Development
Pathways			Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)	Lymphocyte counts ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010)
Interacting Genes		148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 C2CD6 C4orf45 C9orf24 CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PPP1R32 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3	39 interacting genes: AGTRAP AK8 ARFIP2 CCDC57 CEP76 CMTM4 CTAG1A CTAG1B DGAT2L6 FNTB GOLGA2 GSG1 HSF2BP INCA1 KRT31 KRT34 KRTAP10-8 MTUS2 NFKBID PFDN5 PHF1 PLEKHG4 PNMA3 PPP2R3C PRKAR1B RASSF10 REL SLC17A9 SLC50A1 SYP TCF4 TRAF2 TRIM23 TRIM27 TRIP6 TSC1 TTC19 ZMYND12 ZNF655
Entrez ID		284001	56006
HPRD ID		14150	07800
Ensembl ID		ENSG00000176155	ENSG00000105771
Uniprot IDs		A0A590UJT6 Q2TAC2	A0A024R0Q0 Q9H0W8
PDB IDs			6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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