SSH2 and BIRC5

		SSH2	BIRC5
Description		slingshot protein phosphatase 2	baculoviral IAP repeat containing 5
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytoskeleton	Nuclear Chromosome Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Spindle Microtubule Midbody Chromosome Passenger Complex
	Molecular Function	Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding Microtubule Binding Enzyme Binding Small GTPase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Chaperone Binding
	Biological Process	Protein Dephosphorylation Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Polymerization Peptidyl-tyrosine Dephosphorylation	Protein Phosphorylation Apoptotic Process Cell Cycle Chromosome Segregation Sensory Perception Of Sound Positive Regulation Of Cell Population Proliferation Protein-containing Complex Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Cell Division Regulation Of Cell Cycle
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation
Drugs			Reserpine Berberine LY2181308
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coffee consumption (cups per day) ( 25288136) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 28869591) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lung function (FEV1/FVC) ( 30804560) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Peak expiratory flow ( 30804560) Red blood cell count ( 32888494) White blood cell count ( 32888494 27863252)	Blood trace element (Se levels) ( 23720494) Periodontitis (Mean PAL) ( 24024966)
Interacting Genes		3 interacting genes: ACTB BIRC5 CFL1	34 interacting genes: AANAT AKAP6 AURKA AURKB AURKC BIRC2 BIRC3 BIRC6 CASP3 CASP7 CASP9 CCDC85B CDCA8 CDK1 CDK4 CSNK1D DIABLO EVI5 FASN FBXL7 GCGR H3-4 H3C14 HSP90AA1 INCENP KCNJ6 NNMT OGT RAN RASA1 SSH2 TLE3 XIAP XPO1
Entrez ID		85464	332
HPRD ID		09487	04520
Ensembl ID		ENSG00000141298	ENSG00000089685
Uniprot IDs		A0A3B3ITS1 B4DK64 F5H527 Q76I76	A0A0B4J1S3 H3BLT4 O15392
PDB IDs		2NT2	1E31 1F3H 1XOX 2QFA 2RAW 2RAX 3UEC 3UED 3UEE 3UEF 3UEG 3UEH 3UEI 3UIG 3UIH 3UII 3UIJ 3UIK 4A0I 4A0J 4A0N 6SHO 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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