EAF1 and SEMG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EAF1	SEMG1
Description		ELL associated factor 1	semenogelin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Extracellular Region Extracellular Space Nucleus Protein-containing Complex Extracellular Exosome
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Insemination Antibacterial Humoral Response Killing Of Cells Of Other Organism Sperm Capacitation Coagulation Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Calcium Ion Import Positive Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Flagellated Sperm Motility
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Antimicrobial peptides Amyloid fiber formation
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Malaria ( 31844061)
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	9 interacting genes: EAF1 KLK2 KLK3 PRKCA PTPRF SEMG2 TGM1 UBQLN2 UBQLN4
Entrez ID		85403	6406
HPRD ID		12209	01641
Ensembl ID		ENSG00000144597	ENSG00000124233
Uniprot IDs		Q96JC9	P04279
PDB IDs
Enriched GO Terms of Interacting Partners?
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